Phenytoin risk factors
Webpred 2 dňami · People who switch from brand-name Dilantin to generic phenytoin possibly risk having more seizures or side effects during the changeover, because the body does … WebPhenytoin, a widely used antiepileptic drug, has a narrow therapeutic index and large inter-patient variability, partly due to CYP2C9 genetic variation. Patients with the CYP2C9 poor metabolizer phenotype may require reduced doses of phenytoin. Additionally, the HLA-B*15:02 variant is associated with an increased risk of phenytoin-induced ...
Phenytoin risk factors
Did you know?
Web1. dec 2006 · No significant difference was observed for the concentration of GCF phenytoin between responders and non-responders. However, the concentration of plasma …
WebHeadaches Feeling drowsy, sleepy or dizzy Feeling nervous, unsteady or shaky Feeling or being sick (nausea or vomiting) Constipation Sore or swollen gums Some side effects of … Web15. sep 2008 · However, some risk factors are common to all nephrotoxins and include age older than 60 years, underlying renal insufficiency (e.g., GFR of less than 60 mL per minute …
Web15. jan 2024 · The different risk factors for phenytoin toxicity are as follows: Change in Medications . Phenytoin toxicity can occur from an increase in the daily dose of … Web29. júl 2024 · In general, adults appear to be at higher risk for DILI than children. However, children are not without risk as DILI has been reported with use of valproic acid, anticonvulsants, antimicrobials, and aspirin. Children are more susceptible than adults to liver injury associated with propylthiouracil [ 16 ].
Web1. dec 2006 · Conclusion: This study showed that plasma phenytoin level appeared to be a risk factor for phenytoin-induced gingival overgrowth. Citing Literature Volume 77, Issue 12 December 2006 Pages 2005-2010 Information
Web18. okt 2024 · Possible risk factors include young or advanced age, female gender, use of small-bore IV catheters, preexisting cardiovascular disease, multiple or large doses, and rapid rates of IV infusion. ... (oral anticonvulsants, including phenytoin, may increase risk of suicidal thoughts or actions in about 1 in 500 people). Importance of patients ... alchemical astrologyWebThe severity of the hyperplasia increased with increasing dose, increasing dose per unit body weight and serum levels of phenytoin and also with decreasing age and weight of the patients and no significant relationship was found between serum folate levels and degree ofhyperplasia. A survey was carried out into the degree of gingival hyperplasia in 68 … alchemical artWeb23. sep 2024 · The risk factors includes acute severe pancreatitis, sepsis, shock, stroke and alcohol consumption. These multivariable risk factors may precipitate MOD. We … alchemical bag minecraftWeb1. júl 2001 · As the major causes were related to poor follow-up or were iatrogenic, a better patient education and a stepwise dose increase based on serum level, together with drug … alchemical baseWeb15. sep 2024 · The pharmacogenomic basis of phenytoin-related severe cutaneous adverse reactions remains unknown.Objective To investigate the genetic factors associated with … alchemical animalsWeb1. dec 2024 · Limited evidence suggests that HLA-B*1502 may be a risk factor for the development of SJS/TEN in patients of Asian ancestry taking other antiepileptic drugs associated with SJS/TEN, including phenytoin. … alchemical base conanWebThe elevated serum homocysteine is a crucial risk factor for atherosclerosis, cerebrovascular diseases and fetal malformations. [8,9] The pathological process of the … alchemical base conan farming