Thiamine triphosphatase
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Thiamine triphosphatase
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WebCYTH proteins make up a large superfamily that is conserved in all three domains of life. These enzymes have a triphosphate tunnel metalloenzyme (TTM) fold, which typically … WebFunctions. hydrolase activity / magnesium ion binding / thiamin-triphosphatase activity. Processes. dephosphorylation / generation of precursor metabolites and energy / …
It has been shown that in brain ThTP is synthesized in mitochondria by a chemiosmotic mechanism, perhaps similar to ATP synthase. In mammals, ThTP is hydrolyzed to thiamine pyrophosphate (ThDP) by a specific thiamine-triphosphatase. It can also be converted into ThDP by thiamine-diphosphate kinase. Web23 Jan 2007 · Function Hydrolase highly specific for thiamine triphosphate (ThTP). Catalytic activity H2O + thiamine triphosphate = H+ + phosphate + thiamine diphosphate 1 …
Webfunctions as a thiamine triphosphatase and catalyzes the conversion of thiamine triphosphate to thiamine diphos-phate (Lakaye et al., 2004). Triphosphate tunnel metalloen-zyme proteins from fungi, protozoa and some viruses act as RNA triphosphatases (Shuman, 2002). The yeast cap-ping enzyme RNA triphosphatase, Cet1, catalyzes the first Web22 Aug 2013 · Docking thiamin triphosphate into the active site of thiamin triphosphatase does not reveal the thiamin V-conformation either [83]. These structural data provide the …
WebThe encoded protein requires divalent cations for enzymatic activity. The gene product is believed to play a role in regulation of thiamine triphosphate intracellular concentration, …
WebThiamine triphosphate (ThTP) is also found in low amounts in most vertebrate tissues and can phosphorylate certain proteins. Here we show that ThTP exists not only in … meas elpf-t3m-500nWebThe Partial Purification of Thiamine Triphosphatase from Rat Brain Yoshito Hashitani, Jack R. Cooper Journal of Biological Chemistry 1972-04-10 247 (7): 2117-2119 被引量:40 meas cucina schwerteWebThiamine triphosphatase has a pH optimum of 6.8 and is dependent on Mg 2+. The real substrate of the enzyme is probably a 1:1 complex of Mg 2+ and thiamine triphosphate. … meas france toulouseWeb4 Apr 2024 · Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent … meas franceWebThiamine triphosphate (ThTP) is present in low amounts in most organisms from bacteria to humans, but its biological role remains unknown. Escherichia coli grown aerobically in LB … peel the banana kid songWeb无机焦磷酸酶(英語: Inorganic Pyrophosphatase ,简称为焦磷酸酶)是一种催化一分子焦磷酸盐转化为两分子磷酸盐离子的酶 。 这是一个高放能的反应,因此此反应可偶联到一 … meas fx29WebThiamine triphosphate Thiamine triphosphate Identifiers CAS number 3475-65-8 PubChem 18989 MeSH Thiamine+triphosphate SMILES CC1=C(SC=[N+]1CC2=CN= My watch list. ... In mammals, ThTP is hydrolyzed by a specific thiamine triphosphatase. History. Thiamine triphosphate (ThTP) was chemically synthesized in 1948 at a time when the only organic ... peel the banana dance